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Arylglycine-derivative synthesis via oxidative sp(3) C–H functionalization of α-amino esters

An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with α-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives...

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Detalles Bibliográficos
Autores principales: Xu, Zhanwei, Yu, Xiaoqiang, Feng, Xiujuan, Bao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510987/
https://www.ncbi.nlm.nih.gov/pubmed/23209487
http://dx.doi.org/10.3762/bjoc.8.178
Descripción
Sumario:An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with α-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives in satisfactory yields.