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Synthetic studies towards bottromycin

Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion. The intramolecular approach allows the synthesis o...

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Autores principales: Ackermann, Stefanie, Lerchen, Hans-Georg, Häbich, Dieter, Ullrich, Angelika, Kazmaier, Uli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510998/
https://www.ncbi.nlm.nih.gov/pubmed/23209498
http://dx.doi.org/10.3762/bjoc.8.189
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author Ackermann, Stefanie
Lerchen, Hans-Georg
Häbich, Dieter
Ullrich, Angelika
Kazmaier, Uli
author_facet Ackermann, Stefanie
Lerchen, Hans-Georg
Häbich, Dieter
Ullrich, Angelika
Kazmaier, Uli
author_sort Ackermann, Stefanie
collection PubMed
description Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion. The intramolecular approach allows the synthesis of the bottromycin ring system in a straightforward manner.
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spelling pubmed-35109982012-12-03 Synthetic studies towards bottromycin Ackermann, Stefanie Lerchen, Hans-Georg Häbich, Dieter Ullrich, Angelika Kazmaier, Uli Beilstein J Org Chem Full Research Paper Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion. The intramolecular approach allows the synthesis of the bottromycin ring system in a straightforward manner. Beilstein-Institut 2012-10-01 /pmc/articles/PMC3510998/ /pubmed/23209498 http://dx.doi.org/10.3762/bjoc.8.189 Text en Copyright © 2012, Ackermann et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Ackermann, Stefanie
Lerchen, Hans-Georg
Häbich, Dieter
Ullrich, Angelika
Kazmaier, Uli
Synthetic studies towards bottromycin
title Synthetic studies towards bottromycin
title_full Synthetic studies towards bottromycin
title_fullStr Synthetic studies towards bottromycin
title_full_unstemmed Synthetic studies towards bottromycin
title_short Synthetic studies towards bottromycin
title_sort synthetic studies towards bottromycin
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510998/
https://www.ncbi.nlm.nih.gov/pubmed/23209498
http://dx.doi.org/10.3762/bjoc.8.189
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