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Enantioselective total synthesis of (R)-(−)-complanine

A route is described for the enantioselective synthesis of (R)-(−)-complanine, a marine natural product isolated from Eurythoe complanata, and known to be a causative agent in inflammation. An organocatalytic, asymmetric oxyamination of a homoconjugated all-Z-dienal intermediate provides versatile a...

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Detalles Bibliográficos
Autores principales: Kamanos, Krystal A D, Withey, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511001/
https://www.ncbi.nlm.nih.gov/pubmed/23209501
http://dx.doi.org/10.3762/bjoc.8.192