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Organocatalytic cascade aza-Michael/hemiacetal reaction between disubstituted hydrazines and α,β-unsaturated aldehydes: Highly diastereo- and enantioselective synthesis of pyrazolidine derivatives

The catalytic synthesis of nitrogen-containing heterocycles is of great importance to medicinal and synthetic chemists, and also a challenge for modern chemical methodology. In this paper, we report the synthesis of pyrazolidine derivatives through a domino aza-Michael/hemiacetal sequence with chira...

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Detalles Bibliográficos
Autores principales:	Geng, Zhi-Cong, Chen, Jian, Li, Ning, Huang, Xiao-Fei, Zhang, Yong, Zhang, Ya-Wen, Wang, Xing-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2012
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511004/ https://www.ncbi.nlm.nih.gov/pubmed/23209504 http://dx.doi.org/10.3762/bjoc.8.195

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