Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines

In this work we developed C(2)-symmetric chiral nucleophilic catalysts which possess a pyrrolidinopyridine framework as a catalytic site. Some of these organocatalysts effectively promoted asymmetric desymmetrization of meso-diols via enantioselective acylation.

Detalles Bibliográficos
Autores principales: Schedel, Hartmut, Kan, Keizo, Ueda, Yoshihiro, Mishiro, Kenji, Yoshida, Keisuke, Furuta, Takumi, Kawabata, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511012/
https://www.ncbi.nlm.nih.gov/pubmed/23209512
http://dx.doi.org/10.3762/bjoc.8.203
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author Schedel, Hartmut
Kan, Keizo
Ueda, Yoshihiro
Mishiro, Kenji
Yoshida, Keisuke
Furuta, Takumi
Kawabata, Takeo
author_facet Schedel, Hartmut
Kan, Keizo
Ueda, Yoshihiro
Mishiro, Kenji
Yoshida, Keisuke
Furuta, Takumi
Kawabata, Takeo
author_sort Schedel, Hartmut
collection PubMed
description In this work we developed C(2)-symmetric chiral nucleophilic catalysts which possess a pyrrolidinopyridine framework as a catalytic site. Some of these organocatalysts effectively promoted asymmetric desymmetrization of meso-diols via enantioselective acylation.
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spelling pubmed-35110122012-12-03 Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines Schedel, Hartmut Kan, Keizo Ueda, Yoshihiro Mishiro, Kenji Yoshida, Keisuke Furuta, Takumi Kawabata, Takeo Beilstein J Org Chem Full Research Paper In this work we developed C(2)-symmetric chiral nucleophilic catalysts which possess a pyrrolidinopyridine framework as a catalytic site. Some of these organocatalysts effectively promoted asymmetric desymmetrization of meso-diols via enantioselective acylation. Beilstein-Institut 2012-10-17 /pmc/articles/PMC3511012/ /pubmed/23209512 http://dx.doi.org/10.3762/bjoc.8.203 Text en Copyright © 2012, Schedel et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Schedel, Hartmut
Kan, Keizo
Ueda, Yoshihiro
Mishiro, Kenji
Yoshida, Keisuke
Furuta, Takumi
Kawabata, Takeo
Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines
title Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines
title_full Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines
title_fullStr Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines
title_full_unstemmed Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines
title_short Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines
title_sort asymmetric desymmetrization of meso-diols by c(2)-symmetric chiral 4-pyrrolidinopyridines
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511012/
https://www.ncbi.nlm.nih.gov/pubmed/23209512
http://dx.doi.org/10.3762/bjoc.8.203
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