Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene

A new chiral Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions.

Detalles Bibliográficos
Autores principales: Rueping, Magnus, Raja, Sadiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511017/
https://www.ncbi.nlm.nih.gov/pubmed/23209517
http://dx.doi.org/10.3762/bjoc.8.208
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author Rueping, Magnus
Raja, Sadiya
author_facet Rueping, Magnus
Raja, Sadiya
author_sort Rueping, Magnus
collection PubMed
description A new chiral Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions.
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spelling pubmed-35110172012-12-03 Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene Rueping, Magnus Raja, Sadiya Beilstein J Org Chem Full Research Paper A new chiral Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions. Beilstein-Institut 2012-10-23 /pmc/articles/PMC3511017/ /pubmed/23209517 http://dx.doi.org/10.3762/bjoc.8.208 Text en Copyright © 2012, Rueping and Raja https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Rueping, Magnus
Raja, Sadiya
Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
title Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
title_full Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
title_fullStr Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
title_full_unstemmed Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
title_short Asymmetric Brønsted acid-catalyzed aza-Diels–Alder reaction of cyclic C-acylimines with cyclopentadiene
title_sort asymmetric brønsted acid-catalyzed aza-diels–alder reaction of cyclic c-acylimines with cyclopentadiene
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511017/
https://www.ncbi.nlm.nih.gov/pubmed/23209517
http://dx.doi.org/10.3762/bjoc.8.208
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