Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring

A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Shao, Yutian, Li, Kang, Xia, Wujiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511026/
https://www.ncbi.nlm.nih.gov/pubmed/23209526
http://dx.doi.org/10.3762/bjoc.8.217
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author Yang, Chao
Shao, Yutian
Li, Kang
Xia, Wujiong
author_facet Yang, Chao
Shao, Yutian
Li, Kang
Xia, Wujiong
author_sort Yang, Chao
collection PubMed
description A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one. Compound 1, 2 and 3 exhibited appreciable cytotoxic activity against cultured HeLa cells (human cervical carcinoma cells), as well as significant antioxidant activity.
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spelling pubmed-35110262012-12-03 Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring Yang, Chao Shao, Yutian Li, Kang Xia, Wujiong Beilstein J Org Chem Letter A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one. Compound 1, 2 and 3 exhibited appreciable cytotoxic activity against cultured HeLa cells (human cervical carcinoma cells), as well as significant antioxidant activity. Beilstein-Institut 2012-11-05 /pmc/articles/PMC3511026/ /pubmed/23209526 http://dx.doi.org/10.3762/bjoc.8.217 Text en Copyright © 2012, Yang et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Yang, Chao
Shao, Yutian
Li, Kang
Xia, Wujiong
Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_full Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_fullStr Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_full_unstemmed Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_short Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_sort bioactive selaginellins from selaginella tamariscina (beauv.) spring
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511026/
https://www.ncbi.nlm.nih.gov/pubmed/23209526
http://dx.doi.org/10.3762/bjoc.8.217
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