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Total synthesis and biological evaluation of fluorinated cryptophycins

Cryptophycins are cytotoxic natural products that exhibit considerable activities even against multi-drug-resistant tumor cell lines. As fluorinated pharmaceuticals have become more and more important during the past decades, fluorine-functionalized cryptophycins were synthesized and evaluated in ce...

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Detalles Bibliográficos
Autores principales:	Weiß, Christine, Bogner, Tobias, Sammet, Benedikt, Sewald, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2012
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511040/ https://www.ncbi.nlm.nih.gov/pubmed/23209540 http://dx.doi.org/10.3762/bjoc.8.231

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