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Bioreducible and acid-labile poly(amido amine)s for efficient gene delivery
Intracellular processes, including endosomal escape and intracellular release, are efficiency-determining steps in achieving successful gene delivery. It has been found that the presence of acid-labile units in polymers can facilitate endosomal escape and that the presence of reducible units in poly...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511192/ https://www.ncbi.nlm.nih.gov/pubmed/23209367 http://dx.doi.org/10.2147/IJN.S37334 |