Hepatitis C Virus Mediated Changes in miRNA-449a Modulates Inflammatory Biomarker YKL40 through Components of the NOTCH Signaling Pathway

Liver disease due to hepatitis C virus (HCV) infection is an important health problem worldwide. HCV induced changes in microRNAs (miRNA) are shown to mediate inflammation leading to liver fibrosis. Gene expression analyses identified dysregulation of miRNA-449a in HCV patients but not in alcoholic...

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Detalles Bibliográficos
Autores principales: Sarma, Nayan J., Tiriveedhi, Venkataswarup, Subramanian, Vijay, Shenoy, Surendra, Crippin, Jeffrey S., Chapman, William C., Mohanakumar, Thalachallour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511274/
https://www.ncbi.nlm.nih.gov/pubmed/23226395
http://dx.doi.org/10.1371/journal.pone.0050826

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