Cargando…

Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast

BACKGROUND: Lysine-specific demethylase1 (LSD1) is a nuclear protein which belongs to the aminooxidase-enzymes playing an important role in controlling gene expression. It has also been found highly expressed in several human malignancies including breast carcinoma. Our aim was to detect LSD1 expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Serce, Nuran, Gnatzy, Annette, Steiner, Susanne, Lorenzen, Henning, Kirfel, Jutta, Buettner, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511290/ https://www.ncbi.nlm.nih.gov/pubmed/22920283 http://dx.doi.org/10.1186/1472-6890-12-13

Ejemplares similares

Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases
por: Kim, Dongha, et al.
Publicado: (2021)

Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer
por: Majello, Barbara, et al.
Publicado: (2019)

Lysine-specific histone demethylase 1A (LSD1) in cervical cancer
por: Beilner, Daniel, et al.
Publicado: (2020)

Lysine-Specific Demethylase 1 (LSD1) epigenetically controls osteoblast differentiation
por: Rummukainen, Petri, et al.
Publicado: (2022)

The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in Schizosaccharomyces pombe
por: Marayati, Bahjat F., et al.
Publicado: (2020)

Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors
por: Shi, Ying, et al.
Publicado: (2018)

Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A Computational Study
por: Kong, Xiangqian, et al.
Publicado: (2011)

Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies
por: Chao, Angel, et al.
Publicado: (2017)

Lysine-Specific Demethylase 1 (LSD1)-Mediated Epigenetic Modification of Immunogenicity and Immunomodulatory Effects in Breast Cancers
por: Lee, Dong Yeul, et al.
Publicado: (2023)

The Epigenetic Controller Lysine-Specific Demethylase 1 (LSD1) Regulates the Outcome of Hepatitis C Viral Infection
por: Papadopoulou, Georgia, et al.
Publicado: (2023)

Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway
por: Ambrosio, S, et al.
Publicado: (2017)

Lysine-Specific Demethylase 1 (LSD1/KDM1A) Inhibition as a Target for Disease Modification in Myelofibrosis
por: Gill, Harinder
Publicado: (2022)

Lysine-Specific Demethylase 1 (LSD1) Is Required for the Transcriptional Repression of the Telomerase Reverse Transcriptase (hTERT) Gene
por: Zhu, Qingjun, et al.
Publicado: (2008)

Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma
por: Amente, Stefano, et al.
Publicado: (2015)

Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression
por: Chen, Lin, et al.
Publicado: (2017)

Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines
por: Konovalov, Sergiy, et al.
Publicado: (2013)

OR04-3 Lysine-Specific Demethylase-1 (LSD1) Deficiency Increases Aldosterone Signaling via Mineralocorticoid Receptor Activation
por: Treesaranuwattana, Thitinan, et al.
Publicado: (2019)

Functional Interaction of Histone Deacetylase 5 (HDAC5) and Lysine-specific Demethylase 1 (LSD1) Promotes Breast Cancer Progression
por: Cao, Chunyu, et al.
Publicado: (2016)

Nitroreductase‐Mediated Release of Inhibitors of Lysine‐Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells
por: Herrlinger, Eva‐Maria, et al.
Publicado: (2020)

Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes
por: Padalino, Gilda, et al.
Publicado: (2023)

Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
por: He, Pengxing, et al.
Publicado: (2022)

Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis
por: Sun, Qunyan, et al.
Publicado: (2016)

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni
por: Coutinho Carneiro, Vitor, et al.
Publicado: (2020)

Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines
por: Welch, Darcy, et al.
Publicado: (2019)

Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)
por: Sakane, Naoki, et al.
Publicado: (2011)

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)
por: Li, Zhonghua, et al.
Publicado: (2019)

Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases
por: Ambrosio, Susanna, et al.
Publicado: (2018)

A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1
por: Prusevich, Polina, et al.
Publicado: (2014)

Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells
por: Hino, Shinjiro, et al.
Publicado: (2016)

Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis
por: Tamaoki, Junya, et al.
Publicado: (2020)

Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation
por: Antona, Annamaria, et al.
Publicado: (2023)

Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates
por: Itoh, Yukihiro, et al.
Publicado: (2014)

The histone demethylase LSD1/KDM1A promotes the DNA damage response
por: Mosammaparast, Nima, et al.
Publicado: (2013)

Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis
por: Gahan, James M., et al.
Publicado: (2022)

Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models
por: Rapanelli, Maximiliano, et al.
Publicado: (2022)

Demethylase-independent roles of LSD1 in regulating enhancers and cell fate transition
por: Zeng, Cheng, et al.
Publicado: (2023)

Lysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells
por: Feng, Shujun, et al.
Publicado: (2016)

Inhibition of Lysine-Specific Demethylase-1 (LSD1/KDM1A) Promotes the Adipogenic Differentiation of hESCs Through H3K4 Methylation
por: Xiong, Yujing, et al.
Publicado: (2016)

LSD1: more than demethylation of histone lysine residues
por: Perillo, Bruno, et al.
Publicado: (2020)

Correction: Gill, H. Lysine-Specific Demethylase 1 (LSD1/KDM1A) Inhibition as a Target for Disease Modification in Myelofibrosis. Cells 2022, 11, 2107
por: Gill, Harinder
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o4hs5atsqfqitc97aon5kqqh7m