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Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats
Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and immunocompromised individuals. The lack of a safe and effective RSV vaccine represents a major unmet medical need. RSV fusion (F) surface glyco...
Autores principales: | Smith, Gale, Raghunandan, Rama, Wu, Yingyun, Liu, Ye, Massare, Michael, Nathan, Margret, Zhou, Bin, Lu, Hanxin, Boddapati, Sarathi, Li, Jingning, Flyer, David, Glenn, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511306/ https://www.ncbi.nlm.nih.gov/pubmed/23226404 http://dx.doi.org/10.1371/journal.pone.0050852 |
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