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In Vivo Imaging and Quantification of Carbonic Anhydrase IX Expression as an Endogenous Biomarker of Tumor Hypoxia

Carbonic anhydrase IX (CA IX) is a transmembrane protein that has been shown to be greatly upregulated under conditions of hypoxia in many tumor cell lines. Tumor hypoxia is associated with impaired efficacy of cancer therapies making CA IX a valuable target for preclinical and diagnostic imaging. W...

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Detalles Bibliográficos
Autores principales:	Bao, Bagna, Groves, Kevin, Zhang, Jun, Handy, Emma, Kennedy, Paul, Cuneo, Garry, Supuran, Claudiu T., Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511310/ https://www.ncbi.nlm.nih.gov/pubmed/23226406 http://dx.doi.org/10.1371/journal.pone.0050860

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