Cargando…
The Scribble Polarity Protein Stabilizes E-Cadherin/p120-Catenin Binding and Blocks Retrieval of E-Cadherin to the Golgi
Several polarity proteins, including Scribble (Scrb) have been implicated in control of vesicle traffic, and in particular the endocytosis of E-cadherin, but through unknown mechanisms. We now show that depletion of Scrb enhances endocytosis of E-cadherin by weakening the E-cadherin-p120catenin inte...
Autores principales: | Lohia, Madhura, Qin, Yi, Macara, Ian G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511384/ https://www.ncbi.nlm.nih.gov/pubmed/23226478 http://dx.doi.org/10.1371/journal.pone.0051130 |
Ejemplares similares
-
The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin
por: Qin, Yi, et al.
Publicado: (2005) -
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification
por: Pieters, Tim, et al.
Publicado: (2016) -
A novel role for p120 catenin in E-cadherin function
por: Ireton, Reneé C., et al.
Publicado: (2002) -
α-Catenin contributes to the strength of E-cadherin–p120 interactions
por: Troyanovsky, Regina B., et al.
Publicado: (2011) -
Binding site for p120/δ-catenin is not required for Drosophila E-cadherin function in vivo
por: Pacquelet, Anne, et al.
Publicado: (2003)