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Using Plasma Viral Load to Guide Antiretroviral Therapy Initiation to Prevent HIV-1 Transmission
BACKGROUND: Current WHO guidelines recommend antiretroviral therapy (ART) initiation at CD4 counts ≤350 cells/µL. Increasing this threshold has been proposed, with a primary goal of reducing HIV-1 infectiousness. Because the quantity of HIV-1 in plasma is the primary predictor of HIV-1 transmission,...
Autores principales: | Murnane, Pamela M., Hughes, James P., Celum, Connie, Lingappa, Jairam R., Mugo, Nelly, Farquhar, Carey, Kiarie, James, Wald, Anna, Baeten, Jared M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511400/ https://www.ncbi.nlm.nih.gov/pubmed/23250272 http://dx.doi.org/10.1371/journal.pone.0051192 |
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