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Structural and Biochemical Studies on ATP Binding and Hydrolysis by the Escherichia coli RNA Chaperone Hfq

In Escherichia coli the RNA chaperone Hfq is involved in riboregulation by assisting base-pairing between small regulatory RNAs (sRNAs) and mRNA targets. Several structural and biochemical studies revealed RNA binding sites on either surface of the donut shaped Hfq-hexamer. Whereas sRNAs are believe...

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Detalles Bibliográficos
Autores principales: Hämmerle, Hermann, Beich-Frandsen, Mads, Večerek, Branislav, Rajkowitsch, Lukas, Carugo, Oliviero, Djinović-Carugo, Kristina, Bläsi, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511402/
https://www.ncbi.nlm.nih.gov/pubmed/23226421
http://dx.doi.org/10.1371/journal.pone.0050892