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Biochemical Reconstitution of Hemorrhagic-Fever Arenavirus Envelope Glycoprotein-Mediated Membrane Fusion
The membrane-anchored proteins of enveloped viruses form labile spikes on the virion surface, primed to undergo large-scale conformational changes culminating in virus-cell membrane fusion and viral entry. The prefusion form of these envelope glycoproteins thus represents an important molecular targ...
Autores principales: | Thomas, Celestine J., Shankar, Sundaresh, Casquilho-Gray, Hedi E., York, Joanne, Sprang, Stephen R., Nunberg, Jack H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511403/ https://www.ncbi.nlm.nih.gov/pubmed/23226473 http://dx.doi.org/10.1371/journal.pone.0051114 |
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