Sequential Induction of Effector Function, Tissue Migration and Cell Death during Polyclonal Activation of Mouse Regulatory T-Cells

The ability of CD4(+)Foxp3(+) regulatory T-cells (Treg) to produce interleukin (IL)-10 is important for the limitation of inflammation at environmental interfaces like colon or lung. Under steady state conditions, however, few Tregs produce IL-10 ex vivo. To investigate the origin and fate of IL-10...

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Detalles Bibliográficos
Autores principales: Langenhorst, Daniela, Gogishvili, Tea, Ribechini, Eliana, Kneitz, Susanne, McPherson, Kirsty, Lutz, Manfred B., Hünig, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511437/
https://www.ncbi.nlm.nih.gov/pubmed/23226238
http://dx.doi.org/10.1371/journal.pone.0050080

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