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Dual Delivery of Hepatocyte and Vascular Endothelial Growth Factors via a Protease-Degradable Hydrogel Improves Cardiac Function in Rats
Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most common cause of cardiac dysfunction due to local cell death and a temporally regulated inflammatory response. Current therapeutics are limited by delivery vehicles that do not address spatial and temporal aspects of...
Autores principales: | Salimath, Apoorva S., Phelps, Edward A., Boopathy, Archana V., Che, Pao-lin, Brown, Milton, García, Andrés J., Davis, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511447/ https://www.ncbi.nlm.nih.gov/pubmed/23226440 http://dx.doi.org/10.1371/journal.pone.0050980 |
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