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Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways
Modeling of signal transduction pathways plays a major role in understanding cells' function and predicting cellular response. Mathematical formalisms based on a logic formalism are relatively simple but can describe how signals propagate from one protein to the next and have led to the constru...
Autores principales: | Mitsos, Alexander, Melas, Ioannis N., Morris, Melody K., Saez-Rodriguez, Julio, Lauffenburger, Douglas A., Alexopoulos, Leonidas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511450/ https://www.ncbi.nlm.nih.gov/pubmed/23226239 http://dx.doi.org/10.1371/journal.pone.0050085 |
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