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Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways

Modeling of signal transduction pathways plays a major role in understanding cells' function and predicting cellular response. Mathematical formalisms based on a logic formalism are relatively simple but can describe how signals propagate from one protein to the next and have led to the constru...

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Detalles Bibliográficos
Autores principales: Mitsos, Alexander, Melas, Ioannis N., Morris, Melody K., Saez-Rodriguez, Julio, Lauffenburger, Douglas A., Alexopoulos, Leonidas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511450/
https://www.ncbi.nlm.nih.gov/pubmed/23226239
http://dx.doi.org/10.1371/journal.pone.0050085

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