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Insulin-Like Growth Factor-1 Signaling Regulates miRNA Expression in MCF-7 Breast Cancer Cell Line
In breast carcinomas, increased levels of insulin-like growth factor 1 (IGF-1) can act as a mitogen to augment tumorigenesis through the regulation of MAPK and AKT signaling pathways. Signaling through these two pathways allows IGF-1 to employ mechanisms that favor proliferation and cellular surviva...
Autores principales: | Martin, Elizabeth C., Bratton, Melyssa R., Zhu, Yun, Rhodes, Lyndsay V., Tilghman, Syreeta L., Collins-Burow, Bridgette M., Burow, Matthew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511482/ https://www.ncbi.nlm.nih.gov/pubmed/23226206 http://dx.doi.org/10.1371/journal.pone.0049067 |
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