Cargando…

Modulation of Mitochondrial Outer Membrane Permeabilization and Apoptosis by Ceramide Metabolism

The yeast Saccharomyces cerevisiae undergoes a mitochondrial-dependent programmed cell death in response to different stimuli, such as acetic acid, with features similar to those of mammalian apoptosis. However, the upstream signaling events in this process, including those leading to mitochondrial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rego, António, Costa, Margarida, Chaves, Susana Rodrigues, Matmati, Nabil, Pereira, Helena, Sousa, Maria João, Moradas-Ferreira, Pedro, Hannun, Yusuf A., Costa, Vítor, Côrte-Real, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511487/ https://www.ncbi.nlm.nih.gov/pubmed/23226203 http://dx.doi.org/10.1371/journal.pone.0048571

Ejemplares similares

Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death
por: Rego, António, et al.
Publicado: (2020)

Regulation of Cell Death Induced by Acetic Acid in Yeasts
por: Chaves, Susana R., et al.
Publicado: (2021)

Dural MALT lymphoma with disseminated disease
por: Matmati, Kelly, et al.
Publicado: (2010)

Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process
por: Amaral, Leslie, et al.
Publicado: (2020)

C2-Phytoceramide Perturbs Lipid Rafts and Cell Integrity in Saccharomyces cerevisiae in a Sterol-Dependent Manner
por: Pacheco, Andreia, et al.
Publicado: (2013)

Mitochondrial outer membrane permeabilization at the single molecule level
por: Dadsena, Shashank, et al.
Publicado: (2021)

Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway
por: Zeidan, Youssef H., et al.
Publicado: (2008)

Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release
por: Marques, C, et al.
Publicado: (2013)

Cell wall dynamics modulate acetic acid-induced apoptotic cell death of Saccharomyces cerevisiae
por: Rego, António, et al.
Publicado: (2014)

A new twist to the emerging functions of ceramides in cancer: novel role for platelet acid sphingomyelinase in cancer metastasis
por: Hannun, Yusuf A, et al.
Publicado: (2015)

Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells
por: Zhang, Kevin R., et al.
Publicado: (2023)

Analysis of the Involvement of Different Ceramide Variants in the Response to Hydroxyurea Stress in Baker's Yeast
por: Chen, Po-Wei, et al.
Publicado: (2016)

Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells
por: Teixeira, Vitor, et al.
Publicado: (2014)

Dynamics of the Heat Stress Response of Ceramides with Different Fatty-Acyl Chain Lengths in Baker’s Yeast
por: Chen, Po-Wei, et al.
Publicado: (2015)

A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane
por: Greene, Meaghan, et al.
Publicado: (2022)

Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer membrane permeabilization and intrinsic apoptosis
por: Heimer, Sina, et al.
Publicado: (2019)

Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria
por: Farrag, Hala A., et al.
Publicado: (2019)

Metabolic remodeling precedes mitochondrial outer membrane permeabilization in human glioma xenograft cells
por: Ponnala, Shivani, et al.
Publicado: (2021)

The Fate of Acetic Acid during Glucose Co-Metabolism by the Spoilage Yeast Zygosaccharomyces bailii
por: Rodrigues, Fernando, et al.
Publicado: (2012)

Finding pathway-modulating genes from a novel Ontology Fingerprint-derived gene network
por: Qin, Tingting, et al.
Publicado: (2014)

Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides
por: Trayssac, Magali, et al.
Publicado: (2021)

Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced programmed cell death in Saccharomyces cerevisiae
por: Sousa, Marlene, et al.
Publicado: (2013)

VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast
por: Trindade, Dário, et al.
Publicado: (2016)

Identification and Biochemical Characterization of an Acid Sphingomyelinase-Like Protein from the Bacterial Plant Pathogen Ralstonia solanacearum that Hydrolyzes ATP to AMP but Not Sphingomyelin to Ceramide
por: Airola, Michael V., et al.
Publicado: (2014)

VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release
por: Madesh, Muniswamy, et al.
Publicado: (2001)

Outer Membrane Permeabilization Is an Essential Step in the Killing of Gram-Negative Bacteria by the Lectin RegIIIβ
por: Miki, Tsuyoshi, et al.
Publicado: (2013)

Cristae remodeling causes acidification detected by integrated graphene sensor during mitochondrial outer membrane permeabilization
por: Pham, Ted D., et al.
Publicado: (2016)

Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid
por: Kitatani, Kazuyuki, et al.
Publicado: (2015)

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn(2+)-dependent amidases
por: Yi, Jae Kyo, et al.
Publicado: (2022)

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging
por: Jones, E. Ellen, et al.
Publicado: (2014)

Effect of Myricetin, Pyrogallol, and Phloroglucinol on Yeast Resistance to Oxidative Stress
por: Mendes, Vanda, et al.
Publicado: (2015)

The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol
por: Kluck, Ruth M., et al.
Publicado: (1999)

Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes
por: Heesterbeek, Dani A. C., et al.
Publicado: (2021)

Saccharomyces cerevisiae Cells Lacking the Zinc Vacuolar Transporter Zrt3 Display Improved Ethanol Productivity in Lignocellulosic Hydrolysates
por: Terra-Matos, Joana, et al.
Publicado: (2022)

A transcriptional network governing ceramide homeostasis establishes a cytokine-dependent developmental process
por: Liao, Ruiqi, et al.
Publicado: (2023)

Marine Cyanobacteria Compounds with Anticancer Properties: A Review on the Implication of Apoptosis
por: Costa, Margarida, et al.
Publicado: (2012)

Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2
por: Xu, Ruijuan, et al.
Publicado: (2017)

A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation
por: Zhao, Lihong, et al.
Publicado: (2011)

The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
por: Boyd, Rowan A., et al.
Publicado: (2023)

Permeabilized microbes in biotechnology
por: Wackett, Lawrence P
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jg2aj1nnqtmhl554bkofnh47bj