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Structural Requirements for the Procoagulant Activity of Nucleic Acids
Nucleic acids, especially extracellular RNA, are exposed following tissue- or vessel damage and have previously been shown to activate the intrinsic blood coagulation pathway in vitro and in vivo. Yet, no information on structural requirements for the procoagulant activity of nucleic acids is availa...
Autores principales: | Gansler, Julia, Jaax, Miriam, Leiting, Silke, Appel, Bettina, Greinacher, Andreas, Fischer, Silvia, Preissner, Klaus T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511531/ https://www.ncbi.nlm.nih.gov/pubmed/23226277 http://dx.doi.org/10.1371/journal.pone.0050399 |
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