Cargando…

Association between MLH1 -93G>A Polymorphism and Risk of Colorectal Cancer

BACKGROUND: The -93G>A (rs1800734) polymorphism located in the promoter of mismatch repair gene, MLH1, has been identified as a low-penetrance variant for cancer risk. Many published studies have evaluated the association between the MLH1 -93G>A polymorphism and colorectal cancer (CRC) risk. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ting, Liu, Yang, Sima, Li, Shi, Liang, Wang, Zhaoming, Ni, Chunhui, Zhang, Zhengdong, Wang, Meilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511571/ https://www.ncbi.nlm.nih.gov/pubmed/23226285 http://dx.doi.org/10.1371/journal.pone.0050449

Ejemplares similares

Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers
por: Miyakura, Yasuyuki, et al.
Publicado: (2014)

The hMLH1 −93G>A Polymorphism and Risk of Ovarian Cancer in the Chinese Population
por: Niu, Leilei, et al.
Publicado: (2015)

Correction: The hMLH1 −93G>A Polymorphism and Risk of Ovarian Cancer in the Chinese Population
por: Niu, Leilei, et al.
Publicado: (2019)

MLH1–93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAF(V600E) mutation
por: Fennell, Lochlan J., et al.
Publicado: (2018)

The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer
por: Savio, Andrea J., et al.
Publicado: (2017)

Polymorphism of MSH2 Gly322Asp and MLH1 –93G>A in non-familial colon cancer – a case-controlled study
por: Mik, Michal, et al.
Publicado: (2017)

The DNA Repair Gene APE1 T1349G Polymorphism and Risk of Gastric Cancer in a Chinese Population
por: Gu, Dongying, et al.
Publicado: (2011)

MDM2 SNP309 polymorphism is associated with colorectal cancer risk
por: Wang, Weizhi, et al.
Publicado: (2014)

Association study between XPG Asp1104His polymorphism and colorectal cancer risk in a Chinese population
por: Du, Haina, et al.
Publicado: (2014)

Isolated MLH1 Loss by Immunohistochemistry Because of Benign Germline MLH1 Polymorphisms
por: Bosch, Dustin E., et al.
Publicado: (2022)

Associations of IL-4, IL-4R, and IL-13 Gene Polymorphisms in Coal Workers' Pneumoconiosis in China: A Case-Control Study
por: Wang, Meilin, et al.
Publicado: (2011)

Association of MLH1 single nucleotide polymorphisms with clinical outcomes of first-line irinotecan-based chemotherapy in colorectal cancer
por: Wang, Deqiang, et al.
Publicado: (2018)

CD93 gene polymorphism is associated with disseminated colorectal cancer
por: Olsen, Renate S., et al.
Publicado: (2015)

The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability
por: Russell, Holly, et al.
Publicado: (2020)

An inverse association between tea consumption and colorectal cancer risk
por: Chen, Yuetong, et al.
Publicado: (2017)

Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer
por: Wang, Shui-Ming, et al.
Publicado: (2019)

Correction to: The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability
por: Russell, Holly, et al.
Publicado: (2021)

Body mass index (BMI) trajectories and risk of colorectal cancer in the PLCO cohort
por: Zheng, Rui, et al.
Publicado: (2018)

Correlation of MLH1 and MGMT methylation levels between peripheral blood leukocytes and colorectal tissue DNA samples in colorectal cancer patients
por: LI, XIA, et al.
Publicado: (2013)

Characterization of somatic mutations of colorectal tumor in a patient with concurrent APC and MLH1 germline mutations
por: Cheng, Yunsheng, et al.
Publicado: (2023)

Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer
por: Wang, Meilin, et al.
Publicado: (2013)

Association between Two Common Polymorphisms and Risk of Hepatocellular Carcinoma: Evidence from an Updated Meta-Analysis
por: Wang, Zhaoming, et al.
Publicado: (2014)

The polymorphisms of miRNA‐binding site in MLH3 and ERCC1 were linked to the risk of colorectal cancer in a case–control study
por: Zhang, Qianye, et al.
Publicado: (2018)

MLH1 Promoter Methylation Frequency in Colorectal Cancer Patients and Related Clinicopathological and Molecular Features
por: Li, Xia, et al.
Publicado: (2013)

Combinatorial approach of in silico and in vitro evaluation of MLH1 variant associated with Lynch syndrome like metastatic colorectal cancer
por: Saleem, Komal, et al.
Publicado: (2020)

Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway
por: Kim, Jung Ho, et al.
Publicado: (2016)

Relationship Between Human mutL Homolog 1 (hMLH1) Hypermethylation and Colorectal Cancer: A Meta-Analysis
por: Zhang, Hui-Feng, et al.
Publicado: (2017)

Analysis of MLH3 C2531T polymorphism in Iranian women with unexplained infertility
por: Pashaiefar, Hossein, et al.
Publicado: (2013)

Association between the Polymorphism rs3217927 of CCND2 and the Risk of Childhood Acute Lymphoblastic Leukemia in a Chinese Population
por: Zhang, Heng, et al.
Publicado: (2014)

TSP-1-1223 A/G Polymorphism as a Potential Predictor of the Recurrence Risk of Bladder Cancer in a Chinese Population
por: Yang, Xiao, et al.
Publicado: (2013)

Age-Dependent Cancer Risk Is Not Different in between MSH2 and MLH1 Mutation Carriers
por: Olschwang, Sylviane, et al.
Publicado: (2009)

Polymorphism rs2682818 in miR‐618 is associated with colorectal cancer susceptibility in a Han Chinese population
por: Chen, Yuetong, et al.
Publicado: (2018)

Association Between hMLH1 Promoter Methylation and Risk of Gastric Cancer: A Meta-Analysis
por: Ye, Peng, et al.
Publicado: (2018)

Prevalence of Pathological Germline Mutations of hMLH1 and hMSH2 Genes in Colorectal Cancer
por: Li, Dandan, et al.
Publicado: (2013)

G. P. S. Occhialini 1907-93
Publicado: (1994)

The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans
por: Manhart, Carol M., et al.
Publicado: (2017)

Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer
por: Ackermann, Anne, et al.
Publicado: (2019)

The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome
por: Clyne, M, et al.
Publicado: (2009)

Association between MMP-1 g.-1607dupG Polymorphism and Periodontitis Susceptibility: A Meta-Analysis
por: Li, Dandan, et al.
Publicado: (2013)

ADH1C Ile350Val Polymorphism and Cancer Risk: Evidence from 35 Case–Control Studies
por: Xue, Yao, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_d7obq6r5vqaksjsbvqmoo7ts4v