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HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule

New approaches consisting of ‘multistage' vaccines against (TB) are emerging that combine early antigenic proteins with latency-associated antigens. In this study, HspX was tested for its potential to elicit both short- and long-term protective immune responses. HspX is a logical component in v...

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Detalles Bibliográficos
Autores principales: Taylor, Jennifer L, Wieczorek, Agatha, Keyser, Andrew R, Grover, Ajay, Flinkstrom, Rachel, Karls, Russell K, Bielefeldt-Ohmann, Helle, Dobos, Karen M, Izzo, Angelo A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511932/
https://www.ncbi.nlm.nih.gov/pubmed/22801575
http://dx.doi.org/10.1038/icb.2012.34