Cargando…

A Comprehensive Genetic Approach for Improving Prediction of Skin Cancer Risk in Humans

Prediction of genetic risk for disease is needed for preventive and personalized medicine. Genome-wide association studies have found unprecedented numbers of variants associated with complex human traits and diseases. However, these variants explain only a small proportion of genetic risk. Mounting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vazquez, Ana I., de los Campos, Gustavo, Klimentidis, Yann C., Rosa, Guilherme J. M., Gianola, Daniel, Yi, Nengjun, Allison, David B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2012
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512154/ https://www.ncbi.nlm.nih.gov/pubmed/23051645 http://dx.doi.org/10.1534/genetics.112.141705

Ejemplares similares

Modeling Heterogeneity in the Genetic Architecture of Ethnically Diverse Groups Using Random Effect Interaction Models
por: Veturi, Yogasudha, et al.
Publicado: (2019)

Prediction of Expected Years of Life Using Whole-Genome Markers
por: de los Campos, Gustavo, et al.
Publicado: (2012)

Prediction of Complex Human Traits Using the Genomic Best Linear Unbiased Predictor
por: de los Campos, Gustavo, et al.
Publicado: (2013)

Beyond Missing Heritability: Prediction of Complex Traits
por: Makowsky, Robert, et al.
Publicado: (2011)

Prediction of Plant Height in Arabidopsis thaliana Using DNA Methylation Data
por: Hu, Yaodong, et al.
Publicado: (2015)

Deciphering Sex-Specific Genetic Architectures Using Local Bayesian Regressions
por: Funkhouser, Scott A., et al.
Publicado: (2020)

Heritability of pulmonary function estimated from pedigree and whole-genome markers
por: Klimentidis, Yann C., et al.
Publicado: (2013)

Genome-Wide Regression and Prediction with the BGLR Statistical Package
por: Pérez, Paulino, et al.
Publicado: (2014)

Optimal breeding-value prediction using a sparse selection index
por: Lopez-Cruz, Marco, et al.
Publicado: (2021)

Increased Proportion of Variance Explained and Prediction Accuracy of Survival of Breast Cancer Patients with Use of Whole-Genome Multiomic Profiles
por: Vazquez, Ana I., et al.
Publicado: (2016)

Factor analysis models for structuring covariance matrices of additive genetic effects: a Bayesian implementation
por: de los Campos, Gustavo, et al.
Publicado: (2007)

Will Big Data Close the Missing Heritability Gap?
por: Kim, Hwasoon, et al.
Publicado: (2017)

Bayesian Networks Illustrate Genomic and Residual Trait Connections in Maize (Zea mays L.)
por: Töpner, Katrin, et al.
Publicado: (2017)

Local genetic covariance between serum urate and kidney function estimated with Bayesian multitrait models
por: Lupi, Alexa S, et al.
Publicado: (2022)

Comparison Between Linear and Non-parametric Regression Models for Genome-Enabled Prediction in Wheat
por: Pérez-Rodríguez, Paulino, et al.
Publicado: (2012)

A Multiple-Trait Bayesian Lasso for Genome-Enabled Analysis and Prediction of Complex Traits
por: Gianola, Daniel, et al.
Publicado: (2020)

A Bayesian approach for constructing genetic maps when markers are miscoded
por: Rosa, Guilherme JM, et al.
Publicado: (2002)

Multitrait Bayesian shrinkage and variable selection models with the BGLR-R package
por: Pérez-Rodríguez, Paulino, et al.
Publicado: (2022)

Imperfect Linkage Disequilibrium Generates Phantom Epistasis (& Perils of Big Data)
por: de los Campos, Gustavo, et al.
Publicado: (2019)

Whole-Genome Multi-omic Study of Survival in Patients with Glioblastoma Multiforme
por: Bernal Rubio, Yeni L., et al.
Publicado: (2018)

Estimating Genetic Ancestry Proportions from Faces
por: Klimentidis, Yann C., et al.
Publicado: (2009)

Inferring causal phenotype networks using structural equation models
por: Rosa, Guilherme JM, et al.
Publicado: (2011)

Genomic Heritability: What Is It?
por: de los Campos, Gustavo, et al.
Publicado: (2015)

Prediction of biological age and evaluation of genome-wide dynamic methylomic changes throughout human aging
por: Amiri Roudbar, Mahmoud, et al.
Publicado: (2021)

HaploBlocker: Creation of Subgroup-Specific Haplotype Blocks and Libraries
por: Pook, Torsten, et al.
Publicado: (2019)

Modeling relationships between calving traits: a comparison between standard and recursive mixed models
por: de Maturana, Evangelina López, et al.
Publicado: (2010)

Combining genetic resources and elite material populations to improve the accuracy of genomic prediction in apple
por: Cazenave, Xabi, et al.
Publicado: (2021)

Study of factors affecting the incidence of skin cancer in patients after liver transplant
por: Campos, Gabriela Rached, et al.
Publicado: (2017)

Improving skin picking diagnosis among Brazilians: validation of the Skin Picking Impact Scale and development of a photographic instrument()()
por: Xavier, Alice Castro Menezes, et al.
Publicado: (2019)

Genome-Wide Association Studies with a Genomic Relationship Matrix: A Case Study with Wheat and Arabidopsis
por: Gianola, Daniel, et al.
Publicado: (2016)

The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies
por: Klimentidis, Yann C., et al.
Publicado: (2016)

Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans
por: Lin, Liang-Yu, et al.
Publicado: (2018)

Predicting complex traits using a diffusion kernel on genetic markers with an application to dairy cattle and wheat data
por: Morota, Gota, et al.
Publicado: (2013)

Accuracy of Genome-Enabled Prediction in a Dairy Cattle Population using Different Cross-Validation Layouts
por: Pérez-Cabal, M. Angeles, et al.
Publicado: (2012)

Genome-enabled prediction of genetic values using radial basis function neural networks
por: González-Camacho, J. M., et al.
Publicado: (2012)

Piercings in medical students and their effects on the skin
por: Purim, Kátia Sheylla Malta, et al.
Publicado: (2014)

Comprehensive analysis of pathogen-responsive wheat NAC transcription factors: new candidates for crop improvement
por: Vranic, Monika, et al.
Publicado: (2022)

Limited-Variant Screening vs Comprehensive Genetic Testing for Familial Hypercholesterolemia Diagnosis
por: Sturm, Amy C., et al.
Publicado: (2021)

Identification of Allelic Heterogeneity at Type-2 Diabetes Loci and Impact on Prediction
por: Klimentidis, Yann C., et al.
Publicado: (2014)

Differential contribution of genomic regions to marked genetic variation and prediction of quantitative traits in broiler chickens
por: Abdollahi-Arpanahi, Rostam, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7o4iu1dunidoci39ik35tvivg6