Engineering the yeast Yarrowia lipolytica for the production of therapeutic proteins homogeneously glycosylated with Man(8)GlcNAc(2) and Man(5)GlcNAc(2)

BACKGROUND: Protein-based therapeutics represent the fastest growing class of compounds in the pharmaceutical industry. This has created an increasing demand for powerful expression systems. Yeast systems are widely used, convenient and cost-effective. Yarrowia lipolytica is a suitable host that is...

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Detalles Bibliográficos
Autores principales: De Pourcq, Karen, Vervecken, Wouter, Dewerte, Isabelle, Valevska, Albena, Van Hecke, Annelies, Callewaert, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512530/
https://www.ncbi.nlm.nih.gov/pubmed/22548968
http://dx.doi.org/10.1186/1475-2859-11-53

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