Cargando…

Influence of PEGylation and RGD loading on the targeting properties of radiolabeled liposomal nanoparticles

PURPOSE: Liposomes have been proposed to be a means of selectively targeting cancer sites for diagnostic and therapeutic applications. The focus of this work was the evaluation of radiolabeled PEGylated liposomes derivatized with varying amounts of a cyclic arginyl–glycyl–aspartic acid (RGD) peptide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rangger, Christine, Helbok, Anna, von Guggenberg, Elisabeth, Sosabowski, Jane, Radolf, Thorsten, Prassl, Ruth, Andreae, Fritz, Thurner, Gudrun C, Haubner, Roland, Decristoforo, Clemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512544/ https://www.ncbi.nlm.nih.gov/pubmed/23226020 http://dx.doi.org/10.2147/IJN.S36847

Ejemplares similares

Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles
por: Rangger, Christine, et al.
Publicado: (2013)

Novel Bifunctional Cyclic Chelator for (89)Zr Labeling–Radiolabeling and Targeting Properties of RGD Conjugates
por: Zhai, Chuangyan, et al.
Publicado: (2015)

Fusarinine C, a novel siderophore‐based bifunctional chelator for radiolabeling with Gallium‐68
por: Zhai, Chuangyan, et al.
Publicado: (2015)

Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m
por: Klingler, Maximilian, et al.
Publicado: (2019)

Correction: Klingler, M., et al. Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m. Pharmaceuticals 2019, 12, 13
por: Klingler, Maximilian, et al.
Publicado: (2019)

[(68)Ga]FSC-(RGD)(3) a trimeric RGD peptide for imaging α(v)β(3) integrin expression based on a novel siderophore derived chelating scaffold—synthesis and evaluation
por: Knetsch, Peter A., et al.
Publicado: (2015)

Comparison of Ga-68-Labeled Fusarinine C-Based Multivalent RGD Conjugates and [(68)Ga]NODAGA-RGD—In Vivo Imaging Studies in Human Xenograft Tumors
por: Zhai, Chuangyan, et al.
Publicado: (2016)

Radiolabelled Peptides for Positron Emission Tomography and Endoradiotherapy in Oncology †
por: Rangger, Christine, et al.
Publicado: (2020)

[(68)Ga]NODAGA-RGD – Metabolic stability, biodistribution, and dosimetry data from patients with hepatocellular carcinoma and liver cirrhosis
por: Haubner, Roland, et al.
Publicado: (2016)

Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting
por: Klingler, Maximilian, et al.
Publicado: (2018)

Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting: Erratum
por: Klingler, Maximilian, et al.
Publicado: (2019)

Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89
por: Zhai, Chuangyan, et al.
Publicado: (2019)

Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding
por: Summer, Dominik, et al.
Publicado: (2017)

Improved quality control of [(177)Lu]Lu-PSMA I&T
por: Kraihammer, Martin, et al.
Publicado: (2023)

Radiolabeled cyclic RGD peptides as radiotracers for tumor imaging
por: Shi, Jiyun, et al.
Publicado: (2016)

Radiopharmaceutical Formulation and Preclinical Testing of (68)Ga-Labeled DOTA-MGS5 for the Regulatory Approval of a First Exploratory Clinical Trial
por: Hörmann, Anton A., et al.
Publicado: (2021)

Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue
por: Pfister, Joachim, et al.
Publicado: (2015)

Organ Biodistribution of Radiolabelled γδ T Cells Following Liposomal Alendronate Administration in Different Mouse Tumour Models
por: Wang, Julie T-W., et al.
Publicado: (2020)

Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT
por: Zhou, Yang, et al.
Publicado: (2011)

Multimerization results in formation of re-bindable metabolites: A proof of concept study with FSC-based minigastrin imaging probes targeting CCK2R expression
por: Summer, Dominik, et al.
Publicado: (2018)

Radiolabelled peptides for oncological diagnosis
por: Laverman, Peter, et al.
Publicado: (2012)

Radiolabeled Liposomes for Nuclear Imaging Probes
por: Low, Ho Ying, et al.
Publicado: (2023)

Exploiting the Concept of Multivalency with (68)Ga- and (89)Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression
por: Summer, Dominik, et al.
Publicado: (2018)

Interleukin-10: An Anti-Inflammatory Marker To Target Atherosclerotic Lesions via PEGylated Liposomes
por: Almer, Gunter, et al.
Publicado: (2012)

Preparation and evaluation of RGD and TAT co-modified docetaxel-loaded liposome
por: Zhu, Ren, et al.
Publicado: (2017)

Radiolabelling of Antigen and Liposomes for Vaccine Biodistribution Studies
por: Henriksen-Lacey, Malou, et al.
Publicado: (2010)

PEGylated liposomes: immunological responses
por: Mohamed, Marwa, et al.
Publicado: (2019)

From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial
por: Pawlak, Dariusz, et al.
Publicado: (2016)

New Radiolabeled Exendin Analogues Show Reduced Renal Retention
por: Joosten, Lieke, et al.
Publicado: (2023)

Comparison of 99mTc radiolabeled somatostatin antagonist with [(68) Ga]Ga-DOTA-TATE in a patient with advanced neuroendocrine tumor
por: Opalinska, Marta, et al.
Publicado: (2023)

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin α(v)β(3)
por: Chen, Haojun, et al.
Publicado: (2016)

A novel CCK(2)/gastrin receptor-localizing radiolabeled peptide probe for personalized diagnosis and therapy of patients with progressive or metastatic medullary thyroid carcinoma: a multicenter phase I GRAN-T-MTC study
por: Erba, Paola A., et al.
Publicado: (2018)

Pegylated liposomal doxorubicin in ovarian cancer
por: Green, Andrew E, et al.
Publicado: (2006)

Pegylated liposomal doxorubicin in ovarian cancer
por: Strother, Robert, et al.
Publicado: (2009)

Pegylated liposomal doxorubicin for myeloid neoplasms
por: Zhang, Cheng, et al.
Publicado: (2019)

Evidence of Protein Adsorption in Pegylated Liposomes: Influence of Liposomal Decoration
por: Sangrà, Marc, et al.
Publicado: (2017)

Gemcitabine-loaded RGD modified liposome for ovarian cancer: preparation, characterization and pharmacodynamic studies
por: Tang, Zhongyuan, et al.
Publicado: (2019)

Theranostic role of radiolabelled RGD peptide in the treatment of radioiodine-resistant thyroid cancer: A novel agent
por: Vatsa, Rakhee, et al.
Publicado: (2020)

Hydrophobic Drug-Loaded PEGylated Magnetic Liposomes for Drug-Controlled Release
por: Hardiansyah, Andri, et al.
Publicado: (2017)

A Pegylated Liposome Loaded with Raddeanin A for Prostate Cancer Therapy
por: He, Kang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9dqvkvbqdsuhpqmf9h7du7oi2g