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560 Dolichyl Phosphate Dependent Mechanism of Exacerbations in Asthma: P-Glycoprotein Overexpression and E-Cadherin Loss
BACKGROUND: In asthma exacerbations there is a functional hyporesponsiveness of glucocorticoid (FHG) receptors (GR) on T cells, disbalance in activity of IL-2, IL-4, IL-10 and E-cadherin loss. Dolichyl phosphate (DolP) plays an essential role in cytokine synthesis, in constancy of glycoproteins of t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
World Allergy Organization Journal
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512589/ http://dx.doi.org/10.1097/01.WOX.0000411675.19290.f9 |