598 Quality of Life in Patients with Common Variable Immunodeficiency in the Department of Allergy and Clinical Immunology—Centro Medico Nacional Siglo XXI

BACKGROUND: Common variable Immunodeficiency (CVIDs) is characterized by a deficiency in antibody production and also generates enormous morbidity of school absenteeism and dropout or cause layoffs. All chronic diseases affect quality of life of patients, in this particular case CVIDs. The use of instruments like the SF - 36 provides information about the patients' perception of their disease and its environment. The objective is to determine the quality of life of adult patients with CVID who receive replacement therapy through the use of SF-36. METHODS: We conducted a cross-sectional cohort study, which included all patients diagnosed with CVID in our hospital with approval from local research committee F-2011-3601-21. We analyzed the results with descriptive statistics and the SF-36 was used the method of Rand Group. RESULTS: Involving 11 patients with CVID, 4 men and 7 women, average age 30 years (18–53) years. The results show a reduction in quality of life of 65%, without gender difference. However in general we see that men are more affected the physical role 31% and women in the general health 40%, In menthal health assesment, we found that in both genders is more affected in Vitality 55%, and Role Emotional least 84.72%. In relation to physical health, both genders showed greater involvement in aspects of general health 45% and less area affected is physical function 68 %. CONCLUSIONS: CVID patients show a significant deterioration in their quality of life. It's important to highlight that there are not statistically different variations in quality of life. But the general perception of gender does vary without establishing differences between mental and physical health.