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24 Common and Rare Variation in the T Helper 2 Gene Pathway Predicts Allergic Asthma Phenotypes

BACKGROUND: The T helper 2 (Th2) inflammatory pathway, including the Th2-activating cytokine interleukin 33 and its receptor interleukin 1 receptor-like 1 have been strongly implicated in asthma susceptibility (Moffatt MF, et al NEJM 2010). However, the role of Th2 pathway genetic variation in asthm...

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Detalles Bibliográficos
Autores principales: Slager, Rebecca, Moore, Wendy, Li, Huashi, Busse, William, Castro, Mario, Erzurum, Serpil, Fitzpatrick, Anne, Wenzel, Sally, Meyers, Deborah, Bleecker, Eugene R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512652/
http://dx.doi.org/10.1097/01.WOX.0000411769.14940.76

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