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501 Activation of PAR-2 Induces Myofibroblast Transformation via a TGF-β and GSK-3β/β-catenin Dependent Pathway in Tissue Remodeling in the Asthmatic Lung
BACKGROUND: Asthma is a chronic inflammatory lung disease, and airway remodeling denotes the pathophysiologic modifications of normal airway wall structure, including changes in the composition and organization of the airway wall's cellular and molecular constituents. These structural alteratio...
Autores principales: | Suzuki, Tomoko, Downey, Gregory, Nakagome, Kazuyuki, Nagata, Makoto, Hagiwara, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
World Allergy Organization Journal
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512798/ http://dx.doi.org/10.1097/01.WOX.0000411616.11421.94 |
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