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Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer

PURPOSE: To study target-specific delivery of doxorubicin (Dox) using an RNA aptamer against epithelial cell adhesion molecule (EpCAM) in retinoblastoma (RB) cells. METHODS: The binding affinity of the EpCAM aptamer to RB primary tumor cells, Y79 and WERI-Rb1 cells, and Müller glial cell lines were...

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Detalles Bibliográficos
Autores principales:	Subramanian, Nithya, Raghunathan, Vaishnavi, Kanwar, Jagat R., Kanwar, Rupinder K., Elchuri, Sailaja V., Khetan, Vikas, Krishnakumar, Subramanian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513190/ https://www.ncbi.nlm.nih.gov/pubmed/23213278

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