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ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics

BACKGROUND: Genetic variability in ABCB1, encoding the P-glycoprotein efflux transporter, has been linked to altered methadone maintenance treatment dose requirements. However, subsequent studies have indicated that additional environmental or genetic factors may confound ABCB1 pharmacogenetics in d...

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Detalles Bibliográficos
Autores principales:	Barratt, Daniel T, Coller, Janet K, Hallinan, Richard, Byrne, Andrew, White, Jason M, Foster, David JR, Somogyi, Andrew A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513228/ https://www.ncbi.nlm.nih.gov/pubmed/23226062 http://dx.doi.org/10.2147/PGPM.S29272

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