Cargando…

E4 Antibodies Facilitate Detection and Type-Assignment of Active HPV Infection in Cervical Disease

High-risk human papillomavirus (HPV) infections are the cause of nearly all cases of cervical cancer. Although the detection of HPV DNA has proved useful in cervical diagnosis, it does not necessarily predict disease presence or severity, and cannot conclusively identify the causative type when mult...

Descripción completa

Detalles Bibliográficos
Autores principales:	Griffin, Heather, Wu, Zhonglin, Marnane, Rebecca, Dewar, Vincent, Molijn, Anco, Quint, Wim, Van Hoof, Christine, Struyf, Frank, Colau, Brigitte, Jenkins, David, Doorbar, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513315/ https://www.ncbi.nlm.nih.gov/pubmed/23226504 http://dx.doi.org/10.1371/journal.pone.0049974

Ejemplares similares

Stratification of HPV-Induced Cervical Pathology using the Virally-Encoded Molecular Marker E4 in Combination with p16 or MCM
por: Griffin, Heather, et al.
Publicado: (2015)

Whole tissue cervical mapping of HPV infection: Molecular evidence for focal latent HPV infection in humans
por: Hammer, Anne, et al.
Publicado: (2019)

Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124‐2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions
por: Leeman, Annemiek, et al.
Publicado: (2020)

Refining our understanding of cervical neoplasia and its cellular origins
por: Doorbar, John, et al.
Publicado: (2019)

Long-Term Follow-Up of HPV16-Positive Women: Persistence of the Same Genetic Variant and Low Prevalence of Variant Co-Infections
por: Geraets, Daan T., et al.
Publicado: (2013)

Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening
por: Verhoef, Lisanne, et al.
Publicado: (2023)

Efficacy of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical intraepithelial neoplasia and cervical infection in young Japanese women: Open follow-up of a randomized clinical trial up to 4 years post-vaccination
por: Konno, Ryo, et al.
Publicado: (2014)

Evidence of latent HPV infection in older Danish women with a previous history of cervical dysplasia
por: Hammer, Anne, et al.
Publicado: (2022)

Performance of DNA methylation analysis of ASCL1, LHX8, ST6GALNAC5, GHSR, ZIC1 and SST for the triage of HPV‐positive women: Results from a Dutch primary HPV‐based screening cohort
por: Verhoef, Lisanne, et al.
Publicado: (2021)

Performance of HPV E4 and p16(INK4a) biomarkers in predicting regression of cervical intraepithelial neoplasia grade 2 (CIN2): protocol for a historical cohort study
por: Damgaard, Rikke Kamp, et al.
Publicado: (2022)

Type distribution of human papillomavirus among adult women diagnosed with invasive cervical cancer (stage 1b or higher) in New Zealand
por: Sykes, Peter, et al.
Publicado: (2014)

Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples
por: Stevenson, Andrew, et al.
Publicado: (2018)

Human papillomavirus prevalence and type-distribution in women with cervical lesions: a cross-sectional study in Sri Lanka
por: Karunaratne, Kanishka, et al.
Publicado: (2014)

The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines
por: Kranjec, Christian, et al.
Publicado: (2016)

Human Papillomavirus (HPV) Vaccine Effectiveness and Potential Herd Immunity for Reducing Oncogenic Oropharyngeal HPV-16 Prevalence in the United Kingdom: A Cross-sectional Study
por: Mehanna, Hisham, et al.
Publicado: (2019)

Modulation of basal cell fate during productive and transforming HPV‐16 infection is mediated by progressive E6‐driven depletion of Notch
por: Kranjec, Christian, et al.
Publicado: (2017)

Six-Month Incidence and Persistence of Oral HPV Infection in HIV-Negative and HIV-Infected Men Who Have Sex with Men
por: Mooij, Sofie H., et al.
Publicado: (2014)

HPV types, HIV and invasive cervical carcinoma risk in Kampala, Uganda: a case-control study
por: Odida, Michael, et al.
Publicado: (2011)

HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation
por: Yin, Wen, et al.
Publicado: (2023)

Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation
por: Biryukov, Jennifer, et al.
Publicado: (2017)

High prevalence of high-risk HPV genotypes other than 16 and 18 in cervical cancers of Curaçao: implications for choice of prophylactic HPV vaccine
por: Hooi, Desiree J, et al.
Publicado: (2018)

Cervical cell lift: A novel triage method for the spatial mapping and grading of precancerous cervical lesions
por: Shiraz, Aslam, et al.
Publicado: (2022)

Randomized trial evaluating self-sampling for HPV DNA based tests for cervical cancer screening in Nigeria
por: Modibbo, Fatima, et al.
Publicado: (2017)

HPV Type Distribution and Cervical Cytology among HIV-Positive Tanzanian and South African Women
por: Dols, Joke A. M., et al.
Publicado: (2012)

HPV16 and 18 genome amplification show different E4-dependence, with 16E4 enhancing E1 nuclear accumulation and replicative efficiency via its cell cycle arrest and kinase activation functions
por: Egawa, Nagayasu, et al.
Publicado: (2017)

Introduction of primary screening using high-risk HPV DNA detection in the Dutch cervical cancer screening programme: a population-based cohort study
por: Aitken, Clare A., et al.
Publicado: (2019)

Human papillomavirus (HPV) types prevalence in cervical samples of female sex-workers on Curaçao
por: Hooi, Desiree J., et al.
Publicado: (2018)

Human papillomavirus prevalence and type‐distribution in cervical glandular neoplasias: Results from a European multinational epidemiological study
por: Holl, Katsiaryna, et al.
Publicado: (2015)

Clinical performance of high-risk HPV testing on self-samples versus clinician samples in routine primary HPV screening in the Netherlands: An observational study
por: Inturrisi, Federica, et al.
Publicado: (2021)

High prevalence of HPV16 and high‐grade cytology in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2
por: Damgaard, Rikke Kamp, et al.
Publicado: (2023)

Clinical and Analytical Performance of the BD Onclarity HPV Assay with SurePath Screening Samples from the Danish Cervical Screening Program Using the VALGENT Framework
por: Bonde, Jesper Hansen, et al.
Publicado: (2020)

Analysis of cervical HPV infections among unvaccinated young adult women to inform vaccine strategies in this age group: the Costa Rica HPV Vaccine Trial
por: Sierra, Mónica S., et al.
Publicado: (2023)

Monoclonal antibodies in cervical malignancy-related HPV
por: Aghbash, Parisa Shiri, et al.
Publicado: (2022)

Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia
por: Egawa, Nagayasu, et al.
Publicado: (2015)

Type-specific incidence, clearance and predictors of cervical human papillomavirus infections (HPV) among young women: a prospective study in Uganda
por: Banura, Cecily, et al.
Publicado: (2010)

Grading immunohistochemical markers p16(INK4a) and HPV E4 identifies productive and transforming lesions caused by low‐ and high‐risk HPV within high‐grade anal squamous intraepithelial lesions
por: Leeman, A., et al.
Publicado: (2019)

Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections
por: Maglennon, G. A., et al.
Publicado: (2014)

Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI
por: Boers, Ruben, et al.
Publicado: (2018)

Detection of HPV DNA in paraffin-embedded cervical samples: a comparison of four genotyping methods
por: Castro, Felipe A., et al.
Publicado: (2015)

HPV negative cervical cancers and primary HPV screening
por: Tjalma, WAA
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h8duc5suqjc99bfba8uil11cj5