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Disparate roles of marrow- and parenchymal cell-derived TLR4 signaling in murine LPS-induced systemic inflammation

Systemic inflammatory response syndrome (SIRS) occurs in a range of infectious and non-infectious disease processes. Toll-like receptors (TLRs) initiate such responses. We have shown that parenchymal cell TLR4 activation drives LPS-induced systemic inflammation; SIRS does not develop in mice lacking...

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Detalles Bibliográficos
Autores principales:	Juskewitch, Justin E., Platt, Jeffrey L., Knudsen, Bruce E., Knutson, Keith L., Brunn, Gregory J., Grande, Joseph P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513967/ https://www.ncbi.nlm.nih.gov/pubmed/23213355 http://dx.doi.org/10.1038/srep00918

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