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Interaction between Red Yeast Rice and CYP450 Enzymes/P-Glycoprotein and Its Implication for the Clinical Pharmacokinetics of Lovastatin

Red yeast rice (RYR) can reduce cholesterol through its active component, lovastatin. This study was to investigate the pharmacokinetic properties of lovastatin in RYR products and potential RYR-drug interactions. Extracts of three registered RYR products (LipoCol Forte, Cholestin, and Xuezhikang) w...

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Detalles Bibliográficos
Autores principales:	Chen, Chia-Hao, Uang, Yow-Shieng, Wang, Shang-Ta, Yang, Jyh-Chin, Lin, Chun-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513969/ https://www.ncbi.nlm.nih.gov/pubmed/23227093 http://dx.doi.org/10.1155/2012/127043

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