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T granules in human platelets function in TLR9 organization and signaling
Human and murine platelets (PLTs) variably express toll-like receptors (TLRs), which link the innate and adaptive immune responses during infectious inflammation and atherosclerotic vascular disease. In this paper, we show that the TLR9 transcript is specifically up-regulated during pro-PLT producti...
Autores principales: | Thon, Jonathan N., Peters, Christopher G., Machlus, Kellie R., Aslam, Rukhsana, Rowley, Jesse, Macleod, Hannah, Devine, Matthew T., Fuchs, Tobias A., Weyrich, Andrew S., Semple, John W., Flaumenhaft, Robert, Italiano, Joseph E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514030/ https://www.ncbi.nlm.nih.gov/pubmed/22908309 http://dx.doi.org/10.1083/jcb.201111136 |
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