PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome

Previous work has shown that the protein kinase A (PKA)–regulated phosphodiesterase (PDE) 4D3 binds to A kinase–anchoring proteins (AKAPs). One such protein, AKAP9, localizes to the centrosome. In this paper, we investigate whether a PKA–PDE4D3–AKAP9 complex can generate spatial compartmentalization...

Descripción completa

Detalles Bibliográficos
Autores principales: Terrin, Anna, Monterisi, Stefania, Stangherlin, Alessandra, Zoccarato, Anna, Koschinski, Andreas, Surdo, Nicoletta C., Mongillo, Marco, Sawa, Akira, Jordanides, Niove E., Mountford, Joanne C., Zaccolo, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514031/
https://www.ncbi.nlm.nih.gov/pubmed/22908311
http://dx.doi.org/10.1083/jcb.201201059

Ejemplares similares

Ejemplares similares