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Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011
We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514083/ https://www.ncbi.nlm.nih.gov/pubmed/23210643 http://dx.doi.org/10.1186/2162-3619-1-13 |
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author | Ali, Natasha Adil, Salman Naseem Shaikh, Mohammad Usman Moosajee, Munira Masood, Nehal |
author_facet | Ali, Natasha Adil, Salman Naseem Shaikh, Mohammad Usman Moosajee, Munira Masood, Nehal |
author_sort | Ali, Natasha |
collection | PubMed |
description | We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n = 34 (35%), followed by β-Thalassemia major in n = 21 (21.6%) and chronic myeloid leukemia in n = 11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2 ± 3.3 months. |
format | Online Article Text |
id | pubmed-3514083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35140832012-12-05 Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 Ali, Natasha Adil, Salman Naseem Shaikh, Mohammad Usman Moosajee, Munira Masood, Nehal Exp Hematol Oncol Short Report We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n = 34 (35%), followed by β-Thalassemia major in n = 21 (21.6%) and chronic myeloid leukemia in n = 11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2 ± 3.3 months. BioMed Central 2012-05-18 /pmc/articles/PMC3514083/ /pubmed/23210643 http://dx.doi.org/10.1186/2162-3619-1-13 Text en Copyright ©2012 ali et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Report Ali, Natasha Adil, Salman Naseem Shaikh, Mohammad Usman Moosajee, Munira Masood, Nehal Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
title | Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
title_full | Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
title_fullStr | Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
title_full_unstemmed | Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
title_short | Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
title_sort | outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514083/ https://www.ncbi.nlm.nih.gov/pubmed/23210643 http://dx.doi.org/10.1186/2162-3619-1-13 |
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