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An improved respiratory syncytial virus neutralization assay based on the detection of green fluorescent protein expression and automated plaque counting

BACKGROUND: Virus neutralizing antibodies against respiratory syncytial virus (RSV) are considered important correlates of protection for vaccine evaluation. The established plaque reduction assay is time consuming, labor intensive and highly variable. METHODS: Here, a neutralization assay based on...

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Detalles Bibliográficos
Autores principales: van Remmerden, Yvonne, Xu, Fang, van Eldik, Mandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514128/
https://www.ncbi.nlm.nih.gov/pubmed/23114196
http://dx.doi.org/10.1186/1743-422X-9-253

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