Resistance to visceral leishmaniasis is severely compromised in mice deficient of bradykinin B2-receptors

BACKGROUND: Kinins liberated from plasma–borne kininogens, are potent innate stimulatory signals. We evaluated whether resistance to infection by Leishmania (L.) chagasi depends on activation of G-protein coupled bradykinin B2 receptors (B2R). FINDINGS: B2R (−/−) C57BL/6 knock-out (KOB2) and B2R(+/+...

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Detalles Bibliográficos
Autores principales: Nico, Dirlei, Feijó, Daniel Ferreira, Maran, Naiara, Morrot, Alexandre, Scharfstein, Julio, Palatnik, Marcos, Palatnik-de-Sousa, Clarisa Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514163/
https://www.ncbi.nlm.nih.gov/pubmed/23151408
http://dx.doi.org/10.1186/1756-3305-5-261

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