Cargando…

iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations

Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass s...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuhring, Mathias, Renard, Bernhard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514238/
https://www.ncbi.nlm.nih.gov/pubmed/23226516
http://dx.doi.org/10.1371/journal.pone.0050246
_version_ 1782251996355493888
author Kuhring, Mathias
Renard, Bernhard Y.
author_facet Kuhring, Mathias
Renard, Bernhard Y.
author_sort Kuhring, Mathias
collection PubMed
description Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. Thereby, the concurrent analysis of proteomic and genomic data is simplified and proteomic results can directly be compared to genomic data. iPiG is freely available from https://sourceforge.net/projects/ipig/. It is implemented in Java and can be run as a stand-alone tool with a graphical user-interface or integrated into existing workflows. Supplementary data are available at PLOS ONE online.
format Online
Article
Text
id pubmed-3514238
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-35142382012-12-05 iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations Kuhring, Mathias Renard, Bernhard Y. PLoS One Research Article Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. Thereby, the concurrent analysis of proteomic and genomic data is simplified and proteomic results can directly be compared to genomic data. iPiG is freely available from https://sourceforge.net/projects/ipig/. It is implemented in Java and can be run as a stand-alone tool with a graphical user-interface or integrated into existing workflows. Supplementary data are available at PLOS ONE online. Public Library of Science 2012-12-04 /pmc/articles/PMC3514238/ /pubmed/23226516 http://dx.doi.org/10.1371/journal.pone.0050246 Text en © 2012 Kuhring, Renard http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Kuhring, Mathias
Renard, Bernhard Y.
iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
title iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
title_full iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
title_fullStr iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
title_full_unstemmed iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
title_short iPiG: Integrating Peptide Spectrum Matches into Genome Browser Visualizations
title_sort ipig: integrating peptide spectrum matches into genome browser visualizations
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514238/
https://www.ncbi.nlm.nih.gov/pubmed/23226516
http://dx.doi.org/10.1371/journal.pone.0050246
work_keys_str_mv AT kuhringmathias ipigintegratingpeptidespectrummatchesintogenomebrowservisualizations
AT renardbernhardy ipigintegratingpeptidespectrummatchesintogenomebrowservisualizations