Development of a Novel DNA Aptamer Ligand Targeting to Primary Cultured Tumor Endothelial Cells by a Cell-Based SELEX Method

The present study used a spontaneous cell-based SELEX method (Systemic Evolution of Ligands by EXponential Enrichment) to produce DNA aptamers that specifically bind to cell surface proteins or biomarkers produced by primary cultured mouse tumor endothelial cells (mTECs). In solid tumors, new blood...

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Detalles Bibliográficos
Autores principales: Ara, Mst. Naznin, Hyodo, Mamoru, Ohga, Noritaka, Hida, Kyoko, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514264/
https://www.ncbi.nlm.nih.gov/pubmed/23226512
http://dx.doi.org/10.1371/journal.pone.0050174

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