Cargando…
Knockout of the 15 kDa Selenoprotein Protects against Chemically-Induced Aberrant Crypt Formation in Mice
Evidence suggests that selenium has cancer preventive properties that are largely mediated through selenoproteins. Our previous observations demonstrated that targeted down-regulation of the 15 kDa selenoprotein (Sep15) in murine colon cancer cells resulted in the reversal of the cancer phenotype. T...
Autores principales: | Tsuji, Petra A., Carlson, Bradley A., Naranjo-Suarez, Salvador, Yoo, Min-Hyuk, Xu, Xue-Ming, Fomenko, Dmitri E., Gladyshev, Vadim N., Hatfield, Dolph L., Davis, Cindy D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514276/ https://www.ncbi.nlm.nih.gov/pubmed/23226526 http://dx.doi.org/10.1371/journal.pone.0050574 |
Ejemplares similares
-
The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways
por: Tsuji, Petra A., et al.
Publicado: (2015) -
Deficiency in the 15 kDa Selenoprotein Inhibits Human Colon Cancer Cell Growth
por: Tsuji, Petra A., et al.
Publicado: (2011) -
Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity
por: Canter, Jessica A., et al.
Publicado: (2021) -
Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells
por: Bang, Jeyoung, et al.
Publicado: (2015) -
Mouse Models Targeting Selenocysteine tRNA Expression for Elucidating the Role of Selenoproteins in Health and Development
por: Carlson, Bradley A., et al.
Publicado: (2009)