Growth Cone MKK7 mRNA Targeting Regulates MAP1b-Dependent Microtubule Bundling to Control Neurite Elongation

Local mRNA translation in neurons has been mostly studied during axon guidance and synapse formation but not during initial neurite outgrowth. We performed a genome-wide screen for neurite-enriched mRNAs and identified an mRNA that encodes mitogen-activated protein kinase kinase 7 (MKK7), a MAP kina...

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Detalles Bibliográficos
Autores principales: Feltrin, Daniel, Fusco, Ludovico, Witte, Harald, Moretti, Francesca, Martin, Katrin, Letzelter, Michel, Fluri, Erika, Scheiffele, Peter, Pertz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514283/
https://www.ncbi.nlm.nih.gov/pubmed/23226105
http://dx.doi.org/10.1371/journal.pbio.1001439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514283/
https://www.ncbi.nlm.nih.gov/pubmed/23226105
http://dx.doi.org/10.1371/journal.pbio.1001439

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