Mouse Nkrp1-Clr Gene Cluster Sequence and Expression Analyses Reveal Conservation of Tissue-Specific MHC-Independent Immunosurveillance

The Nkrp1 (Klrb1)-Clr (Clec2) genes encode a receptor-ligand system utilized by NK cells as an MHC-independent immunosurveillance strategy for innate immune responses. The related Ly49 family of MHC-I receptors displays extreme allelic polymorphism and haplotype plasticity. In contrast, previous BAC...

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Detalles Bibliográficos
Autores principales: Zhang, Qiang, Rahim, Mir Munir A., Allan, David S. J., Tu, Megan M., Belanger, Simon, Abou-Samra, Elias, Ma, Jaehun, Sekhon, Harman S., Fairhead, Todd, Zein, Haggag S., Carlyle, James R., Anderson, Stephen K., Makrigiannis, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514311/
https://www.ncbi.nlm.nih.gov/pubmed/23226525
http://dx.doi.org/10.1371/journal.pone.0050561

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