Daily administration of low molecular weight heparin increases Hepatocyte Growth Factor serum levels in gynaecological patients: pharmacokinetic parameters and clinical implications

BACKGROUND: Hepatocyte Growth Factor (HGF) enhances cytotoxicity of paclitaxel (PTX) and cisplatin (CDDP) in human ovarian cancer cells. Because of potential pitfalls of HGF exogenous administration, we investigated whether HGF serum concentration might be alternatively raised in vivo by administeri...

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Detalles Bibliográficos
Autores principales: Surbone, Anna, Fuso, Luca, Passera, Roberto, Ferrero, Annamaria, Marchese, Cristiana, Martino, Cosimo, Luchin, Annalisa, Di Renzo, Maria Flavia, Zola, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514394/
https://www.ncbi.nlm.nih.gov/pubmed/22999213
http://dx.doi.org/10.1186/1756-0500-5-517

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