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Carbon nanotube–liposome supramolecular nanotrains for intelligent molecular-transport systems

Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, severa...

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Detalles Bibliográficos
Autores principales: Miyako, Eijiro, Kono, Kenji, Yuba, Eiji, Hosokawa, Chie, Nagai, Hidenori, Hagihara, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514502/
https://www.ncbi.nlm.nih.gov/pubmed/23187626
http://dx.doi.org/10.1038/ncomms2233
Descripción
Sumario:Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.