A Novel Type V TA System Where mRNA for Toxin GhoT is Cleaved by Antitoxin GhoS

Among bacterial toxin/antitoxin (TA) systems, to date no antitoxin has been identified that functions by cleaving toxin mRNA. Here we demonstrate YjdO (renamed GhoT) is a membrane lytic peptide that causes ghost cell formation (lysed cells with damaged membranes) and increases persistence (persister...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxue, Lord, Dana M., Cheng, Hsin-Yao, Osbourne, Devon O., Hong, Seok Hoon, Sanchez-Torres, Viviana, Quiroga, Cecilia, Zheng, Kevin, Herrmann, Torsten, Peti, Wolfgang, Benedik, Michael J., Page, Rebecca, Wood, Thomas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514572/
https://www.ncbi.nlm.nih.gov/pubmed/22941047
http://dx.doi.org/10.1038/nchembio.1062

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